Coleus Forskohlii Herbal Extract

Coleus forskohlii Coleus forskohlii is a perennial member of the mint (Lamiaceae) family and grows in the subtropical temperate climates of India, Nepal, Sri Lanka, and Thailand. Plant height is approximately 1-2 feet. The rootstock is typically golden brown, thick, fibrous, and radially spreading. roots are harvested in the fall, when forskolin is at its most concentrated and the color is the brightest.

Phytoconstituents
The diterpene forskolin, derived from the root of the plant, is the primary constituent in Coleus forskohlii. It was discovered by Western scientists in 1974 and was initially referred to as coleonol. Since that time, as other coleonols and diterpenoids have been identified, the name was changed to forskolin.

Mechanisms of Action
Forskolin's primary mode of action is to increase cyclic adenosine monophosphate (cAMP) and cAMP mediated functions, via activation of the enzyme adenylate cyclase.6 Forskolin has been shown to increase cAMP formation in all eukaryotic cells except sperm, without hormonal activation of adenylate cyclase.7


Savesta Specification

  • Coleus extract from Savesta is available as:
  • Coleus extract forskohlii- 10% Forskolin and Coleus forskohlii- 20% Forskolin


Packing

  • 25kg Double Polylined HPDE Drums.

 

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* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
References available upon request.